| # | Eastern Conference | MP | W | D | L | G | GD | Pts | Form |
|---|---|---|---|---|---|---|---|---|---|
| 1. | Tampa Bay | 14 | 7 | 5 | 2 | 17:9 | 8 | 26 | |
| 2. | Hartford Athletic | 14 | 4 | 6 | 4 | 11:11 | 0 | 18 | |
| 3. | Detroit | 13 | 4 | 4 | 5 | 17:15 | 2 | 16 | |
| 4. | Louisville City | 13 | 4 | 4 | 5 | 25:26 | -1 | 16 | |
| 5. | Pittsburgh | 14 | 4 | 3 | 7 | 13:17 | -4 | 15 | |
| 6. | Charleston | 13 | 4 | 2 | 7 | 16:22 | -6 | 14 | |
| 7. | Miami FC | 14 | 3 | 5 | 6 | 12:21 | -9 | 14 | |
| 8. | Rhode Island | 12 | 4 | 0 | 8 | 15:17 | -2 | 12 | |
| 9. | Loudoun | 12 | 3 | 3 | 6 | 12:20 | -8 | 12 | |
| 10. | Birmingham | 11 | 1 | 4 | 6 | 16:24 | -8 | 7 | |
| 11. | Indy Eleven | 12 | 1 | 3 | 8 | 9:19 | -10 | 6 | |
| 12. | Brooklyn | 13 | 1 | 3 | 9 | 12:36 | -24 | 6 | |
| 13. | Sporting Jax | 14 | 1 | 2 | 11 | 12:35 | -23 | 5 | |
| # | Western Conference | MP | W | D | L | G | GD | Pts | Form |
| 1. | El Paso | 14 | 8 | 2 | 4 | 24:13 | 11 | 26 | |
| 2. | Orange County SC | 13 | 5 | 6 | 2 | 21:22 | -1 | 21 | |
| 3. | New Mexico | 13 | 5 | 4 | 4 | 18:15 | 3 | 19 | |
| 4. | San Antonio | 13 | 4 | 6 | 3 | 15:16 | -1 | 18 | |
| 5. | FC Tulsa | 13 | 4 | 5 | 4 | 18:17 | 1 | 17 | |
| 6. | Las Vegas Lights | 13 | 5 | 1 | 7 | 20:24 | -4 | 16 | |
| 7. | Oakland Roots | 12 | 4 | 4 | 4 | 16:17 | -1 | 16 | |
| 8. | Sacramento Republic | 13 | 3 | 7 | 3 | 13:13 | 0 | 16 | |
| 9. | Lexington | 13 | 4 | 3 | 6 | 21:19 | 2 | 15 | |
| 10. | Colorado Springs | 13 | 4 | 3 | 6 | 17:22 | -5 | 15 | |
| 11. | Phoenix Rising | 13 | 2 | 5 | 6 | 12:20 | -8 | 11 | |
| 12. | Monterey Bay | 13 | 0 | 3 | 10 | 10:26 | -16 | 3 |